High FSH

Elevated FSH
Women are born with all the eggs that they will ever have,
and they lose them constantly throughout life until menopause,
when none remain.
The term "ovarian reserve" is useful in the field of
reproductive medicine. It is an estimate of the reserve of the
woman's ovaries - remaining egg supply - to be able to make
babies in the (near) future. In other words, a woman's ovarian
reserve is her remaining fertility potential.
There are several ways to attempt to predict egg quantity and
quality as well as trying to estimate chances for conception
with various forms of fertility treatment. Female age and "day 3
FSH levels are two very important variables. The response of the
ovaries to ovarian stimulation with injectable gonadotropins (FSH)
is another very important variable that affects the overall
chance for conception when in vitro fertilization is attempted.
We have seen different ovarian responses to injectable
gonadotropins depending on the overall health of the woman which
includes the health and patency of her ovarian blood flow.
Blood transports hormones from the endocrine system to target
cells or organs within the body including the hypothalamus,
anterior pituitary and ovaries; the three essential organs
necessary to achieve pregnancy.
If FSH is elevated the first order of business should be to
increase and enhance blood flow so that proper hormonal
distribution is distributed to the ovaries. At the Berkley
Center for Reproductive Wellness & Women’s Health, by employing
acupuncture, and our proprietary herbal formulas, we have
successfully increased blood circulation to the ovaries, and
lowered FSH levels while simultaneously keeping E2 between 25
and 80pg/ml. In other words, our treatments don’t falsely
repress FSH levels, but rather, regulates them.
Further, we have repeatedly seen reduction in the uterine
artery pulsatility index after treatment with acupuncture and
herbs. The pulsatility index is a method of determining the
patency of blood flow to the uterus via the uterine arteries.
The pulsatility index should be < 3 and can be ascertained
through a transvaginal Doppler examination. Women whose
pulsatility index is >3 rarely achieve conception.
Via the release of beta-endorphins from the brain, the
sympathetic nervous system is affected and causes vascular
modulation with dilation of the uterine arteries, thereby
reducing uterine artery impedance and increasing blood flow to
the ovaries.
Antral Follicles
Antral follicles are small follicles (about 2-8 mm in
diameter) that can be seen - and measured and counted - with
ultrasound. Antral follicles are also referred to as resting
follicles. Vaginal ultrasound is the best way to accurately
assess and count these small structures. In my opinion, the
antral follicle counts (in conjunction with female age) are by
far the best tool that is currently available for estimating
ovarian reserve and/or chances for pregnancy with in vitro
fertilization.
Presumably, the number of antral follicles visible on
ultrasound is indicative of the relative number of microscopic
(and sound asleep) primordial follicles remaining in the ovary.
Each primordial follicle contains an immature egg that can
potentially develop in the future. By stimulating blood flow to
these follicles with acupuncture, their health can be improved
and their maturation can be facilitated.
As mentioned above, we now have proof that blood flow to the
entire pelvic environment is increased through the utilization
of acupuncture and herbal medicine. The consensus of Western
physicians is that when there are only a few antral follicles
visible, there are less eggs remaining as compared to when there
are more antral follicles visible. Our view, based on clinical
experience is that even though there may be a ‘few’ antral
follicles present, only one ‘good’ one is required for
conception and that the clinical presentation of poor ovarian
reserve (few antral follicles) often coexists with diminished
egg-quality. By enhancing blood flow to the ovaries we have
repeatedly seen improved egg quality, even in women with low
ovarian reserve. Only one good egg is necessary for conception
to occur.
|
|
FSH Significance |
|
Less than
9 |
Reassuring level. Expect a good response to ovarian
stimulation. |
|
9 - 10 |
Fair.
Response is between completely normal and somewhat
reduced (response varies widely). Overall, a
somewhat reduced live birth rate. |
|
10 - 12 |
Reduced
ovarian reserve. Usually show a reduced response to
stimulation and some reduction in egg and embryo
quality with IVF. Reduced live birth rates on the
average. |
|
12 - 17 |
Generally
show a more marked reduction in response to
stimulation and usually a further reduction in egg
and embryo quality with IVF. Low live birth rates. |
|
Over 17 |
"No go"
level in most clinics. Very poor (or no)
response to stimulation. No live births. "No go"
levels must be individualized for the particular lab
assay and IVF center. |
Many women who visit us present with FSH
levels > 17 and after three to six months of treatment see their
FSH levels reduced to between 6 and 9 with normal E2 levels.
|